Breaking the Blood Brain Barrier: The Quest to Cure Neurodegeneration

Neurological degenerative illnesses like Alzheimer’s, Parkinson’s and ALS have proven difficult to treat because of one of the strongest security systems in the human body: The Blood Brain Barrier. This episode looks at how modern medicine might be able to finally break down that barrier for good. We speak with Jefferies’ Mike Yee, Denali Therapeutics’ Ryan Watts, and Dr. Rachita Sumbria of Chapman University.

The State of Our Union 2022

After three strong years of asset raising and performance, leaders are taking stock of new levers to utilize and opportunities to grow their enterprise values, strengthen their organizations, and stand out in the competitive landscape. The latest State of Our Union takes a deep dive into how changes in capital markets and market structure are impacting investing and business building decisions in 2022.

From Zero to Hero: The Story Behind the mRNA Vaccine

This new season kicks off with a medical breakthrough story you might THINK you know, but isn't so straightforward. The "speedy" development of mRNA technology, behind many Covid-19 vaccines, actually took decades of twists and turns. We speak with Jefferies’ Mike Yee, Acuitas Therapeutics’ Thomas Madden, and Joe Miller of the Financial Times.

Bonus Episode: Hopeless Optimism

Throughout this season, we highlight medical breakthroughs stemming from investment: of time, of money, of research and ingenuity. Exploring the common thread that links all these incredible stories together: the alchemy that brings about these life-saving innovations in healthcare. We speak with Jefferies’ Mike Yee and Will Sevush, Johns Hopkins’ Neeha Zaidi, and Dr. Rachita Sumbria of Chapman University.

Season 3 Trailer: What Healthcare Breakthrough Are You Waiting For?

Invisible Forces is a podcast that investigates the unseen influences that drive our spending, our saving and our global economy. Hosted by Jefferies' insider Shannon Murphy, season three is all about one invisible force – the alchemy that can turn a series of unlikely events, surprises and setbacks into medicine’s biggest successes. We’ll hear from biotech industry leaders and our own Jefferies experts about some of the biggest breakthroughs in medical history – and the investments that brought them into reality.

Understanding Allocators

The Evolution of Fund of Hedge Funds

The Evolution of Fund of Hedge Funds is the second piece in a series to better understand a variety of allocator verticals. We are taking a look at the fund of hedge fund channel; their changing and variant business models, and the value of partnering with these groups.

2021: Year of the Launch?

Emerging Manager Insights

New and emerging managers are providing a critical source of hedge fund industry innovation, and we take a deep dive into these recent trends in 2021: Year of the Launch? Focusing on new entrants, launch timing, rising fees, notable asset flows, and what may lie ahead.

Prime Sustainability Series

Terms, Fees & ESG: Why True Alignment Matters

There is considerable hunger for products classified as an ‘ESG’ or ‘sustainable’ one. We investigate what it means for this diverse array of products and potential alignment of terms, fees, and structure between allocator and managers.

Both Sides of the (Bit) Coin

Who Benefits from Digital Asset Institutionalization

The institutional infrastructure to support crypto-related assets is being built out, and may accelerate broader based acceptance for the asset class over time. Both Sides of the (Bit) Coin unpacks top drivers of this institutionalization and some of the implications as this trend evolves.

Understanding Allocators

The Stability of Wealth

Digging deeper into allocator verticals, Jefferies Capital intelligence is helping GPs and LPs better understand each other. The Stability of Wealth highlights the ins and outs of bank platforms, looking at how they’re structured and how to maximize your partnerships.

Asia On My Mind

Rise of Interest in Asia Based Funds

Why are Asia based managers increasingly top of mind for allocators? We're measuring the highest interest in the region in the past three years, and break down the main drivers behind this trend. Looking at: 1) Growth in Market Cap, 2) Maturation of the Hedge Fund Industry, and 3) Pent up Demand to Travel.

Better Best Practices

Common Sense Communications in the Age of Social Media

Jefferies Capital Intelligence team has received numerous questions on how to adapt and upgrade communication strategies in the era of social media. We dig into how to tell, control and correct a story in 2021. With so many voices – how are managers managing their narratives?