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Prime Services C-Suite Newsletter – October 2024
Regulatory Initiatives, Liquidity Trends, and AI in Relationships
Our newsletter, Jack-of-all-Reads, shares the latest and greatest insights in a brief read on a monthly basis. Please let us know of any comments or questions – we welcome and appreciate your continued partnership.
It’s Not Where, it’s What: Targeted Oncology and the Keys to Solving Cancer
Rather than treating cancer based on its location in the body, scientists have found another, more effective, more targeted way to treat cancer — one that you need a code to unlock. On this episode we look at the surprising history and the hopeful future of immunotherapy, and how the genetic code of cancer itself is being used. We speak with Jefferies’ Mike Yee, Johns Hopkins’ Neeha Zaidi, and Neville Sanjana from the NY Genome Center.S3:EP5
20:39
When Your Home is the Hospital: Tech-Enabled Healing
One of the fastest-growing areas of healthcare is focusing less on what’s wrong with you, but where the healing actually happens. In this episode we learn about innovation beyond the drugs – how doctors are providing medical care right to a patient’s front door. We speak with Jefferies’ Brian Tanquilut, Medically Home’s Raphael Rakowski, and Professor and author Elizabeth Krupinski of Emory University.S3:EP4
19:44
Cracking the Code that Runs Us: The Future of Gene Therapy
The discovery of DNA in the 1850’s allowed us to see into the genetic code of individual humans. Fast forward to the 21st century, scientists are developing a technique to rewrite those genes. In this episode, we look at the ways gene editing is being used to turn that century-old breakthrough into the future of medicine. We speak with Jefferies’ Will Sevush, Beam Therapeutics’ Pino Ciarmella, Neville Sanjana from the NY Genome Center, and Dr. Paul Offit at the Children’s Hospital of Philadelphia.S3:EP3
19:39
Breaking the Blood Brain Barrier: The Quest to Cure Neurodegeneration
Neurological degenerative illnesses like Alzheimer’s, Parkinson’s and ALS have proven difficult to treat because of one of the strongest security systems in the human body: The Blood Brain Barrier. This episode looks at how modern medicine might be able to finally break down that barrier for good. We speak with Jefferies’ Mike Yee, Denali Therapeutics’ Ryan Watts, and Dr. Rachita Sumbria of Chapman University.S3:EP2
18:25
From Zero to Hero: The Story Behind the mRNA Vaccine
This new season kicks off with a medical breakthrough story you might THINK you know, but isn't so straightforward. The "speedy" development of mRNA technology, behind many Covid-19 vaccines, actually took decades of twists and turns. We speak with Jefferies’ Mike Yee, Acuitas Therapeutics’ Thomas Madden, and Joe Miller of the Financial Times.S3:EP1
18:40
Bonus Episode: Hopeless Optimism
Throughout this season, we highlight medical breakthroughs stemming from investment: of time, of money, of research and ingenuity. Exploring the common thread that links all these incredible stories together: the alchemy that brings about these life-saving innovations in healthcare. We speak with Jefferies’ Mike Yee and Will Sevush, Johns Hopkins’ Neeha Zaidi, and Dr. Rachita Sumbria of Chapman University.19:23
Season 3 Trailer: What Healthcare Breakthrough Are You Waiting For?
Invisible Forces is a podcast that investigates the unseen influences that drive our spending, our saving and our global economy. Hosted by Jefferies' insider Shannon Murphy, season three is all about one invisible force – the alchemy that can turn a series of unlikely events, surprises and setbacks into medicine’s biggest successes. We’ll hear from biotech industry leaders and our own Jefferies experts about some of the biggest breakthroughs in medical history – and the investments that brought them into reality.S3:EP0
1:31
An All-Encompassing Economy
Nadia Batchelor, the Co-Founder & Co-Head of J-NOBLE – Jefferies Network of Black and Latinx employees, Kristina Liburd (Founder & CEO of Viageur) and Boyuan Gao (Founder & Principle of Project Inkblot), Stephanie Wemusa (VP Diversity & Inclusion at TalVista) and Evie Cheung (Designer at Doblin), explore how the powerful social justice movement in 2020 created lasting changes for businesses and consumers around the world.S2:EP6
25:30
A New Peace of Mind
Jefferies experts Dominic Lester and Ramin Safai, are joined by Christian Cerda, the CEO of Simplisafe and Thomas Smyth, founder and CEO of Trim. In this episode, we explore how this need for fortification has been accelerated by work-from-home orders and lockdowns, and how this year has changed our idea of security for good.S2:EP5
24:03
Lean, Mean and Green: The Future of Sustainable Businesses
Simon Powell, Jon Matuszewski, and Dominic Lester are joined by Tom Quinn, the President of Halio North America, Erin Wallace, the VP of Integrated Marketing at Thred Up and Thrive Market CEO Nick Green, to dig into how tech is powering green innovations in a wide range of industries. We hear from business leaders how this force is not only good for the Earth, but good for your company's bottom line.S2:EP4
22:59
The Changing Face of Urban Space
Jon Matuszewski, Storm Duncan and Nadia Batchelor join from Jefferies to discuss whether the city-dwellers considering swapping skylines for suburbs will really move, and what implications this may have on the future of city space? Taco Carlier, the co-founder of the Dutch e-bike company Van Moof explores what the pandemic might do for the future of urban transportation.S2:EP3
24:05
When Tech is Your Tailor
Jefferies experts Cameron Lester and Jared Holz explore how the shift towards hyper-personalized goods and services is revolutionizing the retail and healthcare landscapes. They are joined by Nick Green, the co-founder and CEO of Thrive Market, Chris Merkle, the co-founder of MIME, and Dr. William Li, a physician and bestselling author of Eat to Beat Disease.S2:EP2
26:35